Posted by: Team Outlander
Posted on 02/18/2025
The healthcare industry is undergoing a massive transformation, driven by innovations in AI, digital health, value-based care, and tech-enabled services. From streamlining patient experiences to optimizing provider workflows, startups are redefining how care is delivered, accessed, and paid for. But building in HealthTech isn’t just about having a great product—it’s about securing partnerships with payers and providers, navigating complex regulatory hurdles, and proving real-world impact. The right investors don’t just bring capital; they bring deep expertise, industry relationships, and the strategic guidance necessary to scale successfully.
That’s why we’ve put together this curated list of 25 top HealthTech venture capital firms actively investing in 2025. These VCs are backing digital health, healthcare SaaS, payer/provider solutions, virtual care, women’s health, end-of-life, and tech-enabled services. More importantly, we’ve detailed how to approach them, giving founders a direct path to securing funding from investors who understand the nuances of scaling in this space.
If you’re building the future of healthcare through technology and innovation, this list is your roadmap to the right investment partners.
Featured Investors: Leura Craig, Abbie Strabala, Deepika Jonnalagadda, and AJ Smith.
Highlighted Investments: Clover Health, Classpass, Medely, and Fidari
Outlander VC is a generalist fund that has been first or early money in multiple high-impact HealthTech companies. In Fund III, Outlander invests at pre-seed and seed, writing initial checks between $500K and $2.5M+. While the firm does not invest in biotech or pharmaceuticals, Outlander is bullish on transformative healthcare technology—backing AI, automation, and deep-tech solutions that redefine how care is delivered, accessed, and optimized.
How to Apply: Fill out this form.
Featured Investors: Anna Fagin, Robert Fuentes, Chris Gosioco, and Andie Steinberg
Highlighted Investments: Eleanor Health, Zing Health, Habitat Health, and Thyme Care
Town Hall Ventures seeks to partner with entrepreneurs who are as passionate as they are about changing the health care system. The fund is aiming to raise $400M for its fourth flagship fund, Town Hall Ventures IV and invests initial checks ranging from $5 to $25M across all stages.
How to Apply: Reach out to the investors focused on deal sourcing listed above – network referrals work best. Learn more on their website.
Featured Investors: Lynne Chou O’Keefe, Chirag Shah, Hong Truong, and Chuka Esiobu
Highlighted Investments: Hims & Hers, Unite Us, Cohere Health, and Folx Health
Define Ventures is one of the largest funds focused on early-stage health tech companies. Define supports companies from incubation to series B.
How to Apply: Reach out to anyone on the investor team – network referrals work best. Learn more on their website.
Featured Investors: Vishal Vasishth and Kahini Shah
Highlighted Investments: Virta, Galileo, Iterative Health and Devoted Health
Obvious Ventures was one of the first VC firms in the world to become a certified B Corp, and it has backed 100+ purpose-driven companies building transformative solutions to the systemic environmental and social challenges of our time. The firm’s three investment pillars are sustainable systems, healthy living and people power.
How to Apply: Reach out to the investors specializing in healthtech listed above – network referrals work best. Learn more on their website.
Featured Investors: Andrew Bouldin, George Curran, and Andy Lutz
Highlighted Investments: Sondermind, Watershed Health, evolvedMD, and Virgo
FCA Venture Partners invests in digital health and technology enabled healthcare services companies across the seed to series B stages writing checks from $2-6M.
How to Apply: Reach out to the investors specializing in healthtech listed above – network referrals work best. Learn more on their website.
Featured Investors: Stephen Knight, Jon Lim, Carl Byers, and Erica Lee
Highlighted Investments: Iora Health, Liazon, Patient Ping, and VitalWare
F Prime Capital, the CVC of Fidelity Investments, is a global venture capital firm that invests in seed through growth stage technology and healthcare companies, focusing on innovation and disruptive growth.
How to Apply: Reach out to the investors specializing in healthtech listed above – network referrals work best. Learn more on their website.
Featured Investors: Bob Kocher, Camille Samuels, Nick Beim, Ethan Batraski
Highlighted Investments: Athenahealth, Devoted Health, Lyra Health, 10x Genomics
Venrock has been a powerhouse in healthcare and technology investing for over 50 years, with deep roots in healthcare IT, biotech, and tech-enabled services. They invest early and at growth stages, with a strong focus on value-based care, digital health, and enterprise SaaS for healthcare.
How to Apply: Reach out to their investment team through referrals. Learn more on their website.
Featured Investors: Glen Bressner, Todd Pietri, Jarred Bressner, and Pierce Crowley
Highlighted Investments: Noom, Tabula Rasa Healthcare, Benefix, and Kaid Health
Activate Venture Partners has invested in over 100 tech-enabled healthcare and applied technology companies at the seed and early stage.
How to Apply: Reach out to the investors specializing in healthtech listed above – network referrals work best. Contact form on their website.
Featured Investors: Blake Wu, Michael Li, Hui Cheng, and Danielle Ezratty
Highlighted Investments: Anterior, Habitat Health, PayZen, and RevSpring
NEA has served as a partner to the founders and teams behind some of the most transformational innovations in healthcare and technology from early seed to the growth stage over the past five decades.
How to Apply: Reach out to the investors specializing in healthtech listed above – network referrals work best. Learn more on their website.
Featured Investors: Alyssa Reisner, Sophia Michaels, and Faraz Rahman
Highlighted Investments: Abridge, Carbon Health, Main Street Health, and Maven
CVS Health Ventures is a corporate venture capital fund that invests in high-potential, early-stage and growth-stage companies focused on making healthcare more accessible, affordable, and simpler.
How to Apply: Reach out to the investors specializing in early stage healthtech listed above – network referrals work best. Fill out the contact form on their website.
Featured Investors: Dusty Lieb, Kurt Sheline, Omair Ahmed, and Jose Guerola
Highlighted Investments: Cityblock, Main Street Health, Upfront Healthcare, Eleanor Health
Echo Health Ventures invests in early to late stage healthcare companies. They have 30+ companies in their current portfolio.
How to Apply: Reach out to any member of the investment team – network referrals work best. Learn more on their website.
Featured Investors: Bill Geary, Victor Lanio, Margaret Malone, and Tara Sullivan
Highlighted Investments: Greater Good Health, Photon Health, Visana Health
Flare Capital Partners is an early-stage healthcare venture capital firm advancing innovation-driven companies to improve positive health outcomes, broaden care access, and lower healthcare costs.
How to Apply: Reach out to any member of their investment team – network referrals work best. Reach out on their website.
Featured Investors: Athena Shea, Ava Soltani, and Keenan McGuire
Highlighted Investments:
B Capital is a multi-stage investment firm supporting a startup’s unique needs throughout the journey from seed to market leadership. Within healthcare, they are focused on healthcare IT & SaaS, digital healthcare, biotechnology and bio IT, and healthcare insurance and payment.
How to Apply: Reach out to a member of the healthtech investment team listed above – network referrals work best. Learn more on their website.
Featured Investors: Matthew Harrigan, Nelson Schubart, Margaret Davidson, and Hunter Hillenmeyer
Highlighted Investments: Maven, Centivo, Stepful, and Octave
Company Ventures predominantly invests in digital health, fintech and enterprise SaaS businesses at pre-seed, seed and series A stages through our funds with a typical check size of ~$500K-$1M.
How to Apply: Reach out to any member of their investment team – network referrals work best. Learn more on their website.
Featured Investors: Carli Sapir, Sophie Reynolds, and Logan Rocket-Munk
Highlighted Investments: Evvy, Contraline, Alloy, and Bea Fertility
Amboy Street Ventures invests in Seed and Series A stages of cutting-edge Women’s Health and Sexual Health startups that address this untapped $1T market opportunity.
How to Apply: Reach out to any member of their investment team – network referrals work best. Learn more on their website.
Featured Investors: Abby Levy, Alan Patricof, Ray Jang, and James Hueston
Highlighted Investments: Seen Health, Carewell, Isaac Health, and Safe Ride Health
Primetime Partners is a leading investor in longevity tech, across healthcare, fintech and consumer. The fund invests in seed stage as well as opportunistic series A companies.
How to Apply: Reach out to any member of their investment team – network referrals work best. Learn more on their website.
Featured Investors: Brenton Fargnoli, Jane Suh, and Omar Njie
Highlighted Investments: Yuvo, Pi Health, Vori Health, and Cascade Health
AlleyCorp Healthcare is one of the most active early-stage investors in New York dedicated to healthcare. As a physician-led team, they build and invest $1-4M entry checks in companies that dramatically improve healthcare across quality, cost, and access from incubation through seed.
How to Apply: Reach out to the investors specializing in healthtech listed above – network referrals work best. Learn more on their website.
Featured Investors: Benjamin Britt, Eric Dobosh, and Trent Myers
Highlighted Investments: Switchboard Health, Joon Care, Yuvo Health, and Inflow
Route 66 Ventures is focused on the Digital Health & Wellness market, investing in early stage idea-driven, technology companies that will change the world in positive ways and impact people’s lives.
How to Apply: Reach out to anyone on the investment team – network referrals work best. Learn more on their website.
Featured Investors: Sam Toole, Marisa Bass, and Bryce Johnson
Highlighted Investments: Healthify, MIRROR, Alma, and Dandelion Health
Primary Ventures is a generalist fund writing checks ranging from $1-6M into NYC-based seed companies. Primary’s impact team actively works alongside portfolio companies to boost their growth by providing deep operational support.
How to Apply: Reach out to the investors specializing in healthtech listed above – network referrals work best. Learn more on their website.
Featured Investors: Mike Cunningham, George Pantazopoulos, Richie Chaikof, and Courtney Good
Highlighted Investments: Alma, Humata Health, Anatomy, and Bunkerhill
Optum Ventures, a CVC of UnitedHealth Group, invests from seed to growth equity with a mission to promote healthcare innovation across the globe. Their 70+ portfolio companies include value-based care delivery, enterprise software and enabling infrastructure, and fintech, among others.
How to Apply: How to Apply: Reach out to any member of their investment team – network referrals work best. Learn more on their website.
Featured Investors: Nasir Qadree and Emily Zhen
Highlighted Investments: Viu Health, Auxa Health, and Seven Starling
Zeal Capital is a Washington, DC-based venture capital fund investing in healthcare, fintech, and the future of work and learning at the seed and series A. Zeal leverages its Inclusive Investing strategy to narrow wealth, skills, and healthcare gaps in the US, and at scale globally.
How to Apply: Reach out to the investors specializing in healthtech listed above – network referrals work best. Learn more on their website.
Featured Investors: Linnea Roberts, Ita Ekpoudom, Katherine Rice, and Elizabeth Valiaveedan
Highlighted Investments: Maven, Midi Health, Julie, and Spring Health
GingerBread Capital invests $150K-$2M+ in the next generation of women founders and entrepreneurs leading high-growth businesses from seed through series C. The fund has an investment focus in companies impacting women’s health.
How to Apply: Reach out to the investors specializing in healthtech listed above – network referrals work best. Learn more on their website.
Featured Investors: Bob Saunders, Michelle Cao, Sarah Manasvit, and Jagoda Rokicka
Highlighted Investments: Amplified Sciences, eBlu Solutions, mPulse Mobile, and Progentec
OCA Ventures invests in seed through series B companies in enterprise software, consumer software, fintech, and digital health with initial check sizes of $1-3M.
How to Apply: Reach out to the investors specializing in healthtech listed above – network referrals work best. Fill out the form on their website.
Featured Investors: Josh Wolfe, Deena Shakir, David Yang
Highlighted Investments: Kalyope, Aera, Cala, Summer
Lux Capital is known for backing bold, frontier-tech companies pushing the boundaries of healthcare, biotech, and deep science. The firm invests across seed to growth stages, with a focus on startups leveraging AI, robotics, and next-gen therapeutics to reshape the healthcare landscape.
How to Apply: Warm introductions work best. Learn more on their website.
Featured Investors: Galym Imanbayev and Shelley Chu
Highlighted Investments: Soda Health, Tennr, Abridge, and Fathom
Lightspeed backs founders early and supports from seed through Series F and beyond.
How to Apply: Reach out to the investors specializing in healthtech listed above – network referrals work best. Learn more on their website.
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